Congenital heart disease impacts society
Congenital heart disease impacts society

Almost 1% of children are born with congenital heart defects. In the US, it is the leading cause of first-year infant death and is responsible for billions of dollars of medical care each year.
Improving CHD diagnosis and treatment
Improving CHD diagnosis and treatment

Understanding the causes of a disease improves treatment, diagnosis, and prevention. Genetic defects are a major cause of CHD.
Uncovering the genetic causes of CHD
Uncovering the genetic causes of CHD

There are a multitude of genetic pathways involved in proper heart development. By characterizing these gene networks, we can discover the genetic causes of CHD.
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We are interested in how genes are regulated during heart formation. Our lab combines bioinformatics and bench biology to uncover how gene networks drive this process. Understanding the molecular mechanisms underlying heart development will help improve diagnosis and treatment of congenital heart disease.